Tumor necrosis factor (TNF), formerly known as TNF-α, is a chemical messenger produced by the immune system that induces inflammation. [5] TNF is produced primarily by activated macrophages, …

Jun 13, 2025 · Its primary function is to help mediate inflammation, a natural process the body uses to protect itself. The discovery of TNF alpha dates back to 1975, when researchers identified a …

Tumor Necrosis Factor Alpha (TNF-α) is a cytokine that acts as an arbitrator of the local tissue environment following injury, and is involved in bone tissue regeneration. It can initiate apoptosis and …

Nov 15, 2022 · In recent years, it became clear that TNF drives inflammatory responses not only directly by inducing inflammatory gene expression but also indirectly by inducing cell death, instigating...

TNF-α plays a multifaceted role in normal physiology that is highly relevant to human health and disease. In the central nervous system (CNS), this cytokine regulates homeostatic functions, such as …

TNF alpha, primarily produced by activated macrophages, is integral to the immune response. It plays a vital role in systemic inflammation, partaking in cellular signaling that regulates immune cells and …

Jul 26, 2025 · Tumor Necrosis Factor-alpha (TNFα), a member of the TNF family, functions as a primary signaling molecule, or ligand. This protein is primarily secreted by activated immune cells like …

Oct 9, 2025 · Your system gets flooded with inflammation, which often means you have too much tumor necrosis factor – specifically, a type called TNF alpha.

Jul 7, 2023 · TNF-α plays a multifaceted role in normal physiology that is highly relevant to human health and disease. In the central nervous system (CNS), this cytokine regulates homeostatic functions, …

When tumor necrosis factor α is secreted, it is known as tumor necrosis factor alpha. It is a special protein present in the organism which plays an important role in inflammation and immunity.