A large retrospective cohort study finds some cardiovascular benefits when HT is started earlier but generally supports guidelines discouraging use in older women.
A study tracking women for more than two decades adds to growing evidence that when menopause hormone therapy is started may influence dementia risk later in life.
We systematically searched PubMed, Scopus, Embase, and Cochrane databases for randomized clinical trials that compared definitive radiotherapy with or without ADT in localized prostate cancer. The ...
England’s National Health Service (NHS) has announced it will block new referrals for gender-affirming hormone therapy for transgender youth under 18, restricting access to evidence-based care and ...
Clinically meaningful activity was observed in 57 patients at 400 mg BID fed, including 11.1-month median PFS and mutation-subtype–agnostic benefit across kinase versus nonkinase PIK3CA variants.