In a two-level factorial experiment, we consider construction of parallel-flats designs with two identical parallel flats that allow estimation of a set of specified ...

Appropriate antithrombotic regimens for patients with atrial fibrillation who have an acute coronary syndrome or have undergone percutaneous coronary intervention (PCI) are unclear. In an ...

A polypill comprising statins, multiple blood-pressure–lowering drugs, and aspirin has been proposed to reduce the risk of cardiovascular disease. Using a 2-by-2-by-2 factorial design, we randomly ...

In our study, there were no differences in cognitive performance between the groups given donepezil or placebo, irrespective of stimulation therapy or standard care. Chapman et al [12] and Matsuda et ...