To obtain high-quality, purified nucleic acids, scientists can use several different methods, including phenol-chloroform extraction, cesium chloride/ethidium bromide (CsCl/EtBr) gradient ...

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

DNA phosphorothioate (PT)-modification, with a non-bridging oxygen in the phosphodiester backbone substituted by sulfur, is an epigenetic marker in prokaryotes and is involved in the bacterial defense ...

DNA is a truly amazing material. Biologically, it is an information storage molecule carrying genetic codes for gene regulation and protein production. It is essentially what life is made of.

Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three ...

The intracellular environment is highly compartmentalized; biomolecules (nucleic acids, proteins, lipids and so on) are spatiotemporally organized to form functional modules, signal pathways and ...

As a molecular biologist, I always enjoy reading articles concerning DNA and RNA. Your excellent article in the April 3, 2023, issue of C&EN (page 18) titled “The Promise of Peptide Nucleic Acids” ...

The primary bottleneck in this procedure is the inability to culture forensically relevant pathogens under laboratory conditions; moreover, nucleic acids may be low quality or damaged, rendering them ...

Nucleic acid technology came of age during COVID-19 with biopharma firms developing, testing, mass producing, and shipping mRNA vaccines in record time. However, as the pandemic ebbs, the industry now ...

insights from industryStefan CairnsProduct Technical Specialist Malvern Panalytical In this interview, Malvern Panalytical Product Technical Specialist, Dr Stefan Cairns, discusses how size exclusion ...