The human genome may contain more protein-coding genes than prior analyses suggested. A study published last month (May 29) on BioRxiv provides an expanded database of approximately 5,000 novel ...
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Hidden DNA weak spot near gene start mutates rapidly

These sequences are extremely prone to mutations and rank among the most functionally important regions in the entire human ...
Despite progress in defining functional elements of noncoding DNA, it is still not fully understood. Researchers, using an experiment that elucidated the function of tens of thousands of noncoding ...
When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...
The study shows that a long non-coding RNA called CISTR-ACT acts as a master regulator of cell size, influencing how large or small cells grow across multiple tissues.
A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...
What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too ...
The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...
What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are ...