Light microscopy is a key tool that scientists use to image cells, organelles, subcellular structures, and molecules such as proteins and nucleic acids. Because visible light leaves biological ...

Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

Researchers have developed a miniature microscope that is designed for high-resolution 3D images inside the brains of living mice. The new, lightweight design could help scientists understand how ...

Overcoming the resolution limit in a light microscope of around half a wavelength of light (about 250 nanometers) is one of the most significant developments in optics. Due to the wave nature of light ...

Fluorescence nanoscopy has transformed our ability to visualize and discover biological structures. In recent years, ultraprecise single-molecule localization techniques such as MINFLUX and RASTMIN ...

Hamamatsu Photonics has released a new multi-channel confocal unit called MAICO ®. This MEMS confocal unit can easily be attached to any microscope to achieve confocal fluorescence microscopy. This ...

Hamamatsu Photonics has succeeded in creating a technology “that upgrades the spatial resolution of two-photon excitation fluorescence microscopy,” the company this week stated. Suited to ...

An international collaboration of researchers developed two new complementary approaches for versatile but precise light intensity measurements in fluorescence imaging systems. Accurate measurements ...

What does the inside of a cell really look like? In the past, standard microscopes were limited in how well they could answer this question. Now, researchers have succeeded in developing a microscope ...

Modern bioassays tend to fall under three common modalities: colorimetric, luminometric or fluorometric. Colorimetric assays record the amount of light absorbed by a reporter compound. This absorbance ...